Artemisinin: Discovery from the Chinese Herbal Garden
نویسندگان
چکیده
This year's Lasker DeBakey Clinical Research Award goes to Youyou Tu for the discovery of artemisinin and its use in the treatment of malaria--a medical advance that has saved millions of lives across the globe, especially in the developing world.
منابع مشابه
Ancient Chinese methods are remarkably effective for the preparation of artemisinin-rich extracts of Qing Hao with potent antimalarial activity.
Ancient Chinese herbal texts as far back as the 4th Century Zhou hou bei ji fang describe methods for the use of Qing Hao (Artemisia annua) for the treatment of intermittent fevers. Today, the A. annua constituent artemisinin is an important antimalarial drug and the herb itself is being grown and used locally for malaria treatment although this practice is controversial. Here we show that the ...
متن کاملApproaches and Recent Developments for the Commercial Production of Semi-synthetic Artemisinin
The antimalarial drug artemisinin is a natural product produced by the plant Artemisia annua. Extracts of A. annua have been used in Chinese herbal medicine for over two millennia. Following the re-discovery of A. annua extract as an effective antimalarial, and the isolation and structural elucidation of artemisinin as the active agent, it was recommended as the first-line treatment for uncompl...
متن کاملArtemisinin-A Gift from Traditional Chinese Medicine to the World (Nobel Lecture).
Malaria has long been a devastating and life-threatening global epidemic disease in human history. Artemisinin, the active substance against malaria, was first isolated and tested in the 1970s in China. The important role played by traditional Chinese medicine in the discovery of artemisinin is described by Y. Tu in her Nobel Lecture.
متن کاملEditorial to the Feature article "Artemisinin anti-malarial drugs in China".
The winning of the 2015 Nobel Prize in Physiology or Medicine by William C. Champbell, Satoshi Omura, and the Chinese scientist Youyou Tu marks their pioneering discoveries of novel therapeutic drugs to treat highly devastating parasitic diseases that mostly affect the world’s poorest populations, such as river blindness, lymphatic filariasis, and malaria. More appreciably, this is also the fir...
متن کاملFrom branch to bedside: Youyou Tu is awarded the 2011 Lasker~DeBakey Clinical Medical Research Award for discovering artemisinin as a treatment for malaria.
The WHO has indicated that in 2009, the most recent year for which data are available, approximately 250 million people were infected with malaria, and nearly one million of those patients succumbed to their infections. But without Youyou Tu (Institute of Materia Medica, Academy of Traditional Chinese Medicine and China Academy of Chinese Medical Sciences) (Figure 1), many of those 249 million ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Cell
دوره 146 شماره
صفحات -
تاریخ انتشار 2011